None
Conditions
Interventions
Conventional UVC Group:The control group received umbilical venous catheterization with conventional umbilical vascular catheters.
NO-Coated UVC Group:The intervention group received umbilical venous catheterization with nitric oxide (NO)-coated umbilical vascular catheters.
Sponsors
Beijing Childrens Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. Gestational age <= 37 weeks; 2. Age at admission < 1 day; 3. Requirement of UVC for venous access.
Exclusion criteria
Exclusion criteria: 1. Pre-existing skin breakdown or infection at the umbilical root; 2. Conditions precluding UVC insertion, including abdominal wall defects, skeletal dysplasia, peritonitis, necrotizing enterocolitis, and congenital diaphragmatic hernia; 3. Documented coagulation disorders or hemorrhagic diseases; 4. Birth weight <= 800 g; 5. Lack of written informed consent from parents or guardians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thrombosis rate within 1 week of UVC dwell time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Catheter-related bloodstream infection rate;UVC tip migration rate;Incidence of UVC-related adverse events;Incidence of umbilical root vascular dilatation;Primary success rate of UVC insertion; | — |
Countries
China
Contacts
Public ContactHei Mingyan
Beijing Childrens Hospital,Capital Medical University
Outcome results
None listed