A Study on the Effects of Low-GI Low-Glycemic High-Fiber Nutritional Meal Replacement Powder Combined with Low-GI Low-Glycemic Fiber-Milled Rice on Body Weight and Metabolic Indicators in Overweight/Obese Patients

A Randomized Controlled Study on the Effects of Low-GI High-Fiber Nutritional Meal Replacement Powder Combined with Low-GI Embryo-Retained Rice on Body Weight and Metabolic Indicators in Overweight/Obese Patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600121624

Enrollment

Unknown

Registered

2026-04-01

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

overweight and obesity

Interventions

treatment group:Youcai Low-Glycemic Index High-Fiber Meal Replacement Combined with Low-GI Embryo-Retained Rice and Standard Diet and Exercise Counseling

control group: Standard Diet and Exercise Counseling

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-70 years, either sex; 2. Body Mass Index (BMI) >=24 kg/m²; 3. Stable body weight (weight change <5% in the past month); 4. Voluntary participation with signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Known diabetes or fasting blood glucose >=7.0 mmol/L, or glycated hemoglobin (HbA1c) >=6.5%; 2. Severe cardiac, hepatic, or renal insufficiency (ALT, AST >2× upper limit of normal, eGFR <60 mL/min); 3. Abnormal thyroid function; 4. Pregnant or lactating women; 5. Use of antibiotics, probiotics, or weight-loss medications within the past month; 6. Currently undergoing other weight-loss treatments or participating in other clinical trials; 7. Allergy to any component of the study foods.

Design outcomes

Primary

Measure	Time frame
Height;Weight;body fat percentage;visceral fat area;	—

Secondary

Measure	Time frame
Waist circumference;hip circumference;blood pressure; heart rate ;muscle mass; fasting blood glucose; fasting insulin;glycated hemoglobin (HbA1c);glycated albumin;intestinal microbiota detection;	—

Countries

China

Contacts

Public ContactYu Liu

Sir Run Run Hospital, Nanjing Medical University

drliuyu@njmu.edu.cn+86 25 8711 5663

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026