Laparoscopic colorectal surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age: 18-60 years old, gender not limited. 2.American Society of Anesthesiologists ASA Classification: Grades I-III; 3.Body mass Index (BMI) : 18.5-28kg/m ²; 4.General anesthesia surgery; 5.Patients who are scheduled to undergo elective laparoscopic colorectal surgery, with an estimated operation time of more than 60 minutes, and who will be transferred to the PACU after the operation; Including any small or large intestine resection, with or without stoma surgery. 6.Consciously abide by the procedures of this test and voluntarily sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Unable to obtain informed consent; 2.Emergency operation; 3.Non-general anesthesia; 4.Known to be allergic to or intolerant to anesthetic drugs; 5.There was acute or chronic pain before the operation or a long-term history of using opioid or non-opioid painkillers. 6.Peripheral or central nervous system disorders; 7.A history of clearly diagnosed mental illness or other neurological or mental illness that affects the judgment of severe cognitive impairment; History of psychotropic drug use; 8.There was a bacterial or viral infection within 3 days before the operation; 9.The basal mean arterial pressure (MAP) is less than 65 mmHg or more than 120 MMHG, the basal heart rate (HR) is less than 40 beats per minute or more than 120 beats per minute, and there is second-degree or greater conduction block. 10.A history of severe underlying diseases (untreated or persistent peripheral or central cardiovascular diseases, severe liver or kidney diseases); 11.Pregnant and lactating women, lactation period; 12.There are contraindications for performing transversus abdominis plane block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average intraoperative remifentanil infusion rate (ug/kg/min); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative complications;QoR-15 score;The time of the first postoperative exhaust;Postoperative pain score;Dosage of postoperative analgesic drugs;Dosage of propofol during the operation;Postoperative hospital stay;extubation time;PACU stay time; | — |
Countries
China
Contacts
The First Affiliated Hospital,Sun Yat-sen University