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Effects of transversus abdominis plane block(TAPB) on Intraoperative Opioid Consumption and Postoperative Recovery in Patients Undergoing Laparoscopic Colorectal Surgery : A Randomized Controlled Trial

Effects of TAPB on Intraoperative Opioid ConsumptionandPostoperative Recovery in Patients Undergoing LaparoscopicColorectal Surgery : A Randomized Controlled Trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121623
Enrollment
Unknown
Registered
2026-04-01
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic colorectal surgery

Interventions

Group C (Control Group):Simple general anesthesia
Group T (Block Group):Ultrasound-guided transversus abdominis plane block was performed after general anesthesia

Sponsors

The First Affiliated Hospital,Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Age: 18-60 years old, gender not limited. 2.American Society of Anesthesiologists ASA Classification: Grades I-III; 3.Body mass Index (BMI) : 18.5-28kg/m ²; 4.General anesthesia surgery; 5.Patients who are scheduled to undergo elective laparoscopic colorectal surgery, with an estimated operation time of more than 60 minutes, and who will be transferred to the PACU after the operation; Including any small or large intestine resection, with or without stoma surgery. 6.Consciously abide by the procedures of this test and voluntarily sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1.Unable to obtain informed consent; 2.Emergency operation; 3.Non-general anesthesia; 4.Known to be allergic to or intolerant to anesthetic drugs; 5.There was acute or chronic pain before the operation or a long-term history of using opioid or non-opioid painkillers. 6.Peripheral or central nervous system disorders; 7.A history of clearly diagnosed mental illness or other neurological or mental illness that affects the judgment of severe cognitive impairment; History of psychotropic drug use; 8.There was a bacterial or viral infection within 3 days before the operation; 9.The basal mean arterial pressure (MAP) is less than 65 mmHg or more than 120 MMHG, the basal heart rate (HR) is less than 40 beats per minute or more than 120 beats per minute, and there is second-degree or greater conduction block. 10.A history of severe underlying diseases (untreated or persistent peripheral or central cardiovascular diseases, severe liver or kidney diseases); 11.Pregnant and lactating women, lactation period; 12.There are contraindications for performing transversus abdominis plane block.

Design outcomes

Primary

MeasureTime frame
Average intraoperative remifentanil infusion rate (ug/kg/min);

Secondary

MeasureTime frame
Incidence of postoperative complications;QoR-15 score;The time of the first postoperative exhaust;Postoperative pain score;Dosage of postoperative analgesic drugs;Dosage of propofol during the operation;Postoperative hospital stay;extubation time;PACU stay time;

Countries

China

Contacts

Public ContactLi Yunsheng

The First Affiliated Hospital,Sun Yat-sen University

mysjz1@163.com+86 20 8775 5766

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026