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The Impact of a Low-Dose Esketamine on Sleep Quality Following Cesarean Section

The Impact of a Low-Dose Esketamine on Sleep Quality Following Cesarean Section: A Randomized Controlled Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121620
Enrollment
Unknown
Registered
2026-04-01
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum Sleep Disturbance

Interventions

Esketamine group:After the fetus is delivered during a cesarean section, the patient is slowly intravenously injected with 0.25mg/kg of esketamine diluted with 5ml
Control group:None

Sponsors

Tianjin Medical University General Hospital, Tianjin, China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 44 Years

Inclusion criteria

Inclusion criteria: 1. Age 18–44 years; 2. Pregnant women at 36–42 weeks gestation, planning a cesarean section; 3. ASA classification I–III; 4. Patients who agree to voluntarily participate in this trial.

Exclusion criteria

Exclusion criteria: 1. Individuals known to be allergic to the drug components of this study or with drug contraindications; 2. ASA classification IV; patients with poorly controlled pregnancy-induced hypertension or pulmonary arterial hypertension during pregnancy; 3. Bronchial asthma, severe hypertension, serious liver and kidney dysfunction, hyperthyroidism, severe cardiovascular and cerebrovascular diseases; 4. BMI > 35 kg/m^2; 5. Poor compliance, unable to complete the trial according to the study protocol; 6. For any reason, situations deemed by the researchers as unsuitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Postpartum sleep disturbance after cesarean delivery;Hospital Anxiety and Depression Scale;

Countries

China

Contacts

Public ContactXie ke liang

Tianjin Medical University General Hospital

406755607@qq.com+86 153 3211 2099

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026