Liver transplantation
Conditions
Sponsors
Beijing Chaoyang Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-75 years 2. Patients who undergo liver transplantation in our department; 3. No surgical contraindications identified in preoperative evaluation; 4. Preoperative evaluation indicates hypersplenism (meeting the following conditions simultaneously): i. Peripheral blood cell reduction (meeting any of the following): PLT 13 cm or spleen volume >350-400 mL; 5. Complete clinical, imaging, and follow-up data of the patient.
Exclusion criteria
Exclusion criteria: 1. Splenectomy or splenic artery embolization performed before transplantation; 2. Ligation of the splenic artery during surgery or splenic artery embolization performed postoperatively; 3. The patient has undergone TIPS or other surgical treatments to reduce portal pressure; 4. Perioperative death; 5. Complicated with hematologic diseases; 6. Others: such as major ethical issues or lack of informed consent;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of refractory hypersplenism at 6 months post-transplantation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Indicators related to the degree of splenic function recovery;Clinical outcomes associated with hypersplenism; | — |
Countries
China
Contacts
Public ContactLang Ren
Beijing Chaoyang Hospital, Capital Medical University
Outcome results
None listed