Obsessive-compulsive disorder (OCD)
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for Obsessive-Compulsive Disorder (OCD) according to the DSM-5, confirmed by two attending psychiatrists or above; 2. Aged 18–60 years, with a male-to-female ratio of approximately 1:1; 3. Right-handed; 4. Educational level of junior high school or above; 5. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score = 16; 6. Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with mental disorders caused by physical diseases or mental disorders caused by psychoactive substances; 2. Individuals with a history of mental retardation, encephalitis, epilepsy, traumatic brain injury, other neurological diseases, or a history of brain surgery, or those with a history of loss of consciousness lasting =5 minutes; 3. Comorbid schizophrenia or other affective disorders during the active phase; 4. Individuals who are currently receiving or have received any form of physical therapy within the past month; 5. Individuals with other severe physical illnesses; 6. Individuals who are uncooperative or unable to complete the required tests as specified; 7. Individuals with contraindications for magnetic resonance imaging (MRI), or those found to have intracranial organic lesions upon scanning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Yale?Brown Obsessive Compulsive Scale (Y?BOCS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Rating ;Clinical Global Impressions ;Behavioral Inhibition / Activation;Cognitive Flexibility Inventory;Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form;Obsessive Beliefs (OBQ-44);Barratt Impulsiveness ; | — |
Countries
China
Contacts
Changchun Sixth Hospital