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Transcranial Temporal Interference Stimulation for Obsessive-Compulsive Disorder: An Exploratory Study of Safety and Preliminary Efficacy

Transcranial Temporal Interference Stimulation for Obsessive-Compulsive Disorder: An Exploratory Study of Safety and Preliminary Efficacy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121617
Enrollment
Unknown
Registered
2026-04-01
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-compulsive disorder (OCD)

Interventions

Sponsors

Changchun Sixth Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for Obsessive-Compulsive Disorder (OCD) according to the DSM-5, confirmed by two attending psychiatrists or above; 2. Aged 18–60 years, with a male-to-female ratio of approximately 1:1; 3. Right-handed; 4. Educational level of junior high school or above; 5. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score = 16; 6. Voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with mental disorders caused by physical diseases or mental disorders caused by psychoactive substances; 2. Individuals with a history of mental retardation, encephalitis, epilepsy, traumatic brain injury, other neurological diseases, or a history of brain surgery, or those with a history of loss of consciousness lasting =5 minutes; 3. Comorbid schizophrenia or other affective disorders during the active phase; 4. Individuals who are currently receiving or have received any form of physical therapy within the past month; 5. Individuals with other severe physical illnesses; 6. Individuals who are uncooperative or unable to complete the required tests as specified; 7. Individuals with contraindications for magnetic resonance imaging (MRI), or those found to have intracranial organic lesions upon scanning.

Design outcomes

Primary

MeasureTime frame
Yale?Brown Obsessive Compulsive Scale (Y?BOCS) score;

Secondary

MeasureTime frame
Hamilton Anxiety Rating ;Clinical Global Impressions ;Behavioral Inhibition / Activation;Cognitive Flexibility Inventory;Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form;Obsessive Beliefs (OBQ-44);Barratt Impulsiveness ;

Countries

China

Contacts

Public ContactMin Wang

Changchun Sixth Hospital

13894888485@163.com+86 431 8196 8536

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026