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Clinical study on right ventricular myocardial fibrosis caused by tricuspid insufficiency combined with speckle tracking ultrasound

Clinical study on right ventricular myocardial fibrosis caused by tricuspid insufficiency combined with speckle tracking ultrasound

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121614
Enrollment
Unknown
Registered
2026-04-01
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tricuspid Regurgitation (TR).

Interventions

TR group:None

Sponsors

The First Hospital of Nanchang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed by echocardiography with moderate or greater tricuspid regurgitation (TR) (according to the American Society of Echocardiography guidelines: effective regurgitant orifice area >= 40 mm^2 or regurgitant volume >= 45 mL); 2. Aged between 18 and 80 years, of any gender; 3. Clear transthoracic echocardiographic images that meet the requirements for speckle tracking echocardiography (STE) analysis (right ventricular free wall clearly visible, frame rate >= 50 frames/second); 4. Voluntarily willing to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Primary cardiomyopathies (such as hypertrophic cardiomyopathy, dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, etc.); 2. Congenital heart disease (such as Ebstein's anomaly, Tetralogy of Fallot, etc.); 3. Acute myocardial infarction or unstable angina within the past 3 months; 4. Moderate or more severe left heart valvular disease (such as aortic stenosis/insufficiency, mitral stenosis/insufficiency); 5. Persistent atrial fibrillation or other serious arrhythmias (affecting the accuracy of STE image analysis); 6. Severe hepatic or renal insufficiency (Child-Pugh class C or eGFR < 30 mL/min/1.73m²); 7. Pregnant or breastfeeding women; 8. Poor ultrasound image quality, unable to meet STE analysis requirements; 9. Expected poor compliance, unable to complete follow-up.

Design outcomes

Primary

MeasureTime frame
Longitudinal strain of the free wall of the right ventricle;

Countries

China

Contacts

Public Contactliuhailan

The First Hospital of Nanchang

13767174121@qq.com+86 791 8886 2361

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026