Gastric adenocarcinoma
Conditions
Interventions
Trial group:Dietary guidance +ONS
Sponsors
lu an shi ren min yi yuan: Lu'an People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old, pathologically diagnosed with gastric adenocarcinoma, and within 1 to 3 months after undergoing D2 radical resection (unifying the surgical approach to reduce confounding factors); 2. The SOX chemotherapy regimen (teggio + oxaliplatin, 21 days as one cycle, unified chemotherapy regimen to control drug effects) is proposed, and it is the first cycle of chemotherapy; 3. Nutritional Risk Screening (NRS 2002) score >=3 points (nutritional risk exists, ensuring the necessity of intervention); 4. Physical Condition Score (ECOG PS) 0-1 point (stable physical condition, able to cooperate with intervention and assessment); 5. Patients and their families have given informed consent and participate voluntarily.
Exclusion criteria
Exclusion criteria: 1. Combined with underlying diseases such as severe liver and kidney dysfunction (Child-Pugh grade C) and heart failure (NYHA grade III-IV); 2. Severe sarcopenia already existed before chemotherapy (skeletal muscle index < 7.0 kg/m^2 in men and < 5.7 kg/m^2 in women); 3. Allergic to the ingredients of oral nutritional supplements (such as whey protein and vitamins); 4. There are conditions such as gastrointestinal obstruction and bleeding that prevent oral intake; 5. The expected survival period is less than 6 months, or there is cognitive impairment that makes it impossible to cooperate with the assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life score;Body composition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum albumin;Serum prealbumin;Gastrointestinal reaction; | — |
Countries
China
Contacts
Public ContactXinghao Ma
lu an shi ren min yi yuan: Lu'an People's Hospital
Outcome results
None listed