Influenza, fever, sore throat, runny nose, etc
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Part 1 (Epidemiological Characteristics Analysis) Inclusion Criteria: (1) The patient visited the fever clinic of our hospital between March 1, 2023, and February 29, 2024. (2) Presented with fever (body temperature >= 37.3°C) accompanied by at least one of the following influenza-like symptoms: 1) Systemic symptoms: headache, dizziness, fatigue, general muscle/joint soreness, loss of appetite, etc. 2) Upper respiratory symptoms: nasal congestion, runny nose, cough, sputum production, etc. 3) Throat-related discomfort: sore throat, itchy throat, dry throat, etc. (3) Completed influenza A/B virus antigen testing on the day of the visit. 2. Part 2 (Case-Control Study) Inclusion Criteria: (1) Influenza-Positive Group: In addition to meeting criteria (1) and (2) in Part 1, the patient must have a positive influenza virus antigen test result and a complete set of routine blood test results. (2) Influenza-Negative Group: In addition to meeting criteria (1) and (2) in Part 1, the patient must have a negative influenza virus antigen test result and a complete set of routine blood test results.
Exclusion criteria
Exclusion criteria: 1. Part 1 (Epidemiological Characteristics Analysis) Exclusion Criteria: (1) Exclusion of duplicate records of patients revisiting for influenza-like symptoms after a confirmed diagnosis (e.g., non-influenza viral infection). (2) Incomplete medical records with missing or illegible key information (such as age, gender, test results, visit time). (3) Invalid or indeterminate antigen test results. 2. Part 2 (Case-Control Study) Exclusion Criteria: (1) Subjects meeting any of the exclusion criteria in Part 1. (2) Patients in either the case or control group lacking complete routine blood test results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall influenza virus positive detection rate;Proportion of influenza A and B types; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic (gender, age) and seasonal (month) distribution characteristics of influenza-positive cases;Differences in clinical symptoms, blood routine indicators, and chest imaging findings between influenza-positive and negative cases; | — |
Countries
China
Contacts
Shanghai General Hospital