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Efficacy and Safety Analysis of Local Incision Injection of a Ropivacaine-Dexamethasone Mixture for Postoperative Analgesia in Pediatric Spinal Deformity Correction Surgery

Efficacy and Safety Analysis of Local Incision Injection of a Ropivacaine-Dexamethasone Mixture for Postoperative Analgesia in Pediatric Spinal Deformity Correction Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121597
Enrollment
Unknown
Registered
2026-04-01
Start date
2026-04-10
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scoliosis

Interventions

Experimental group:The incision infiltration solution consisted of 0.2% ropivacaine combined with 0.025% dexamethasone.
Control group:The incision infiltration solution consisted of 0.2% ropivacaine

Sponsors

Beijing Children's Hospital, National Center for Children's Health, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Hospitalized children aged 4-18 years, with ASA grades I-II; 2. Children scheduled for spinal curvature correction surgery and receiving intravenous patient-controlled analgesia with sufentanil after the surgery; 3. Capable of self-reporting or having it relayed by their family members, and accurately recognizing and expressing the degree of pain; 4. Have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. The legal guardian refused to participate in this study; 2. Children with severe comorbidities, such as cardiac insufficiency; 3. Those with central and/or peripheral nervous system comorbidities; 4. Those who have recently taken hormone-based medications or are allergic to the study drugs; 5. Those with chronic pain or have been using opioid drugs or other painkillers for more than 3 months; 6. Those who have previously undergone spinal surgery or suffered spinal trauma; 7. Those with preoperative incision site infection; 8. Those with cognitive impairment or mental illness that prevents communication.

Design outcomes

Primary

MeasureTime frame
Postoperative opioid consumption;Postoperative Numerical Rating Scale;

Secondary

MeasureTime frame
Postoperative analgesia satisfaction;Postoperative Nausea and Vomiting (PONV) Assessment;Wound Healing Assessment;

Countries

China

Contacts

Public ContactWang Fang

Beijing Children's Hospital, National Center for Children's Health, Capital Medical University

wangfang@bch.com.cn+86 10 5961 6453

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026