Rotator cuff tear
Conditions
Interventions
Twice-Daily Diacerein Group:Take one 50 mg diacerein capsule orally in the morning and one in the evening.
Morning Diacerein Group:Take one 50 mg diacerein capsule orally in the morning.
Evening Diacerein Group:Take one 50 mg diacerein capsule orally in the evening.
Twice-Daily Control Group:Take one placebo capsule orally in the morning and one in the evening.
Morning Control Group:Take one placebo capsule orally in the morning
Evening Control Group:Take one placebo capsule orally in the evening.
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age 50-70 years; (2) Shoulder pain (VAS pain score of 6 or above), accompanied by limited mobility (reduction in range of motion for abduction, elevation, internal rotation, and external rotation by 50%); (3) MRI findings indicating supraspinatus tendon degeneration with a tear less than 1 cm; (4) Symptoms of shoulder pain and limited mobility lasting no more than 3 months.
Exclusion criteria
Exclusion criteria: (1) Presence of underlying diseases such as hypertension and diabetes; (2) MRI findings indicating moderate to large tears of the supraspinatus tendon; (3) History of previous shoulder dislocation; (4) Rotator cuff injury caused by trauma; (5) Moderate to severe shoulder osteoarthritis, Hamada classification grade 3 or above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS) and Numeric Rating Scale (NRS);Specialized physical examination of the shoulder joint (range of motion; Neer sign; Hawkins sign; Empty Can Test; Drop Arm Test);Shoulder MRI examination;Surgical rate; | — |
Countries
China
Contacts
Public ContactZhao Qichun
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed