Central Precocious Puberty
Conditions
Interventions
Retrospective cohort:None
Prospective cohort:None
Sponsors
Capital Children's Medical Center, Capital Medical University
Eligibility
Sex/Gender
All
Age
4 Years to 16 Years
Inclusion criteria
Inclusion criteria: 1. Retrospective Study (1) Previously visited our hospital for "precocious puberty" or "growth retardation"; (2) Complete baseline assessment and follow-up duration of at least 6 months. 2. Prospective Study (1) Visited for growth and development related issues; (2) Complete baseline assessment and follow-up records of >= 6 months; (3) Strictly adhere to follow-up every 3 months, with imaging re-examination once every 6 months; (4) Subjects and/or guardians voluntarily participate and sign informed consent forms.
Exclusion criteria
Exclusion criteria: 1.CPP caused by central organic lesions; 2.Peripheral precocious puberty; 3.Isolated premature thelarche; 4.Major genetic/metabolic/chronic diseases affecting growth; 5.Those who have participated in interventional trials in the past and may affect the outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone age monitoring;Growth velocity;Tanner staging progression;Treatment response and follow-up duration; | — |
Countries
China
Contacts
Public ContactWang Lin
Capital Children's Medical Center, Capital Medical University
Outcome results
None listed