Advanced Solid Tumor
Conditions
Interventions
Gold Standard: Pathologically confirmed EPHA2-positive solid tumor
Index test:Gallium [68Ga]-EPHA2 Bicyclic Peptide Injection Combined with PET/CT Imaging
Sponsors
The First Hospital of Suzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1: Aged 18–75 years, male or female 2: Pathologically confirmed EPHA2-positive solid tumor 3: Presence of measurable lesions 4: ECOG score 0–3 5: Blood routine, liver and renal function, etc., meet the requirements. 6: Female subjects of childbearing potential with negative pregnancy test
Exclusion criteria
Exclusion criteria: 1: Unable to complete PET/CT examination (e.g., claustrophobia). 2: Presence of brain metastasis, uncontrolled underlying diseases, etc. 3: Toxicity from previous anticancer therapy has not recovered to grade 0–1. 4: Active autoimmune diseases. 5: Recently participated in other radiopharmaceutical trials. 6: Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse events;Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactShengming Deng
The First Affiliated Hospital of Soochow University
Outcome results
None listed