Hip fracture
Conditions
Interventions
Bupivacaine liposomal group:Iliofascial block using bupivacaine liposomes
Ropivacaine group:Iliofascial block with ropivacaine
Sponsors
Lishui peoples hospital
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Age:60-90 years; 2.BMI:19-28kg/m^²; 3.Patients undergoing elective unilateral THA surgery; 4.ASA grade: I, II, III;
Exclusion criteria
Exclusion criteria: 1.communication barriers; 2.Preoperative cognitive impairment; 3.Contraindications to deep nerve block, including but not limited to anesthetic drug allergy, coagulation disorders (INR > 1.5 and/or platelet count <70×10^9), injection site infection; 4.Chronic opioid dependence or chronic pain for more than 3 months; 5.Patients with mental illness (including depression, schizophrenia, epilepsy, Parkinson's disease, or Alzheimer's disease) or patients who cannot cooperate in completing the rating scale; 6.Combined with severe heart, lung, liver or kidney dysfunction, such as liver decompensation (Child B/C grade), etc. 7.Other surgeries within 6 months prior to admission; 8.Nerve blocks cannot be performed due to anatomical difficulties in ultrasound scanning;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of neurocognitive impairment at 7 days, 1 month, and 12 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Remedial analgesia;Postoperative hospital stay;Incidence of postoperative delirium (POD) within 7 days after surgery;Cumulative consumption of opioids at 24 and 48 hours after surgery;Time to first get out of bed after surgery;Recovery of quality on the 1st, 2nd, and 3rd postoperative days (QoR-15);Resting and active NRS scores at 2, 4, 8, 24, and 48h after surgery; | — |
Countries
China
Contacts
Public ContactWu Jimim
Lishui peoples hospital
Outcome results
None listed