Cervical squamous epithelial lesion
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The research subjects in the verification stage mainly come from clinical cases including those from Guangdong Provincial Maternal and Child Health Hospital (GWCH). The specific inclusion requirements are as follows: 1. Time span: Clinical samples collected from August 2024 to May 2025. Specimen sources: Covering common clinical specimens such as cervical Biopsy, Conization and total hysterectomy. 2. Image quality: All tissue sections were digitized by high-resolution digital section scanners (such as SQS-600), and the images were clear at 20x magnification. 3. Pathological integrity: Digital full sections (WSI) must include the complete tissue regions required for diagnosis and have clear expert-level control labels (benign, precancerous lesions or cancer subtypes).
Exclusion criteria
Exclusion criteria: 1. Image quality defects: Digital slices have obvious scanning artifacts, blurriness, severe occlusion, or severe tissue wrinkles, which affect feature extraction. 2. Abnormal specimen processing: Severe staining unevenness, excessive decalcification, or fragmented slides occur during tissue preparation, resulting in the inability to identify key morphological features. 3. Non cervical primary tumors: For the task of verifying the diagnosis of specific subtypes of the cervix, exclude all non cervical primary metastatic tumors (excluding specific pelvic pre training studies). 4. Unclear diagnostic opinion: After review by multiple experts and pathologists, consensus cannot be reached and there is controversy over the diagnosis and classification of complex cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Area Under the Curve;Balanced Accuracy;F1 Score; | — |
Countries
China
Contacts
Guangdong Province Hospital for Women and Children Healthcare