colorectal cancer
Conditions
Interventions
Aremefentanil Group:Aremefentanil 1.0 µg/kg is administered before skin incision.
Sufentanil Group:Sufentanil 0.1 µg/kg is administered before skin incision.
Sponsors
Ma'anshan People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective laparoscopic-assisted radical resection for colorectal cancer. 2. Aged 60–85 years. 3. ASA physical status Class I–III. 4. Body mass index (BMI) 18–30 kg/m². 5. Patients undergoing primary surgery. 6. Normal mental status, consciousness and cognitive function. 7. Written informed consent obtained from patients and their families.
Exclusion criteria
Exclusion criteria: 1. patients with severe cardiovascular and cerebrovascular diseases ; 2. Patients with central nervous system injury or craniocerebral trauma. 3. Patients with hepatic or renal insufficiency and coagulation dysfunction. 4. Patients with a history of alcohol abuse or drug abuse. 5. Patients with hypersensitivity to the study drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first ambulation;Time to independent ambulation;Length of hospital stay ;Incidence of postoperative adverse events; | — |
Countries
China
Contacts
Public ContactJing Jun
Ma'anshan People's Hospital
Outcome results
None listed