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A cohort study investigating potential biomarkers in plasma and urine and their diagnostic value in patients with sepsis-associated acute kidney injury

A cohort study investigating potential biomarkers in plasma and urine and their diagnostic value in patients with sepsis-associated acute kidney injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121549
Enrollment
Unknown
Registered
2026-03-31
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis-associated acute kidney injury

Interventions

Sepsis-associated acute kidney injury group:None
Sepsis without acute kidney injury group:None

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old 2. Diagnosed with sepsis (according to Sepsis-3 criteria) 3. Baseline renal function is assessable: Before enrollment, basic data such as Scr/urine volume can be obtained to determine "no AKI occurred at the time of enrollment" 4. Signed informed consent form

Exclusion criteria

Exclusion criteria: 1. Patients with chronic kidney disease: CKD stage 4-5 2. Patients who have undergone long-term renal replacement therapy 3. Patients who have undergone kidney transplantation or solid organ transplantation 4. Patients with clear pre-renal, post-renal or nephrotoxic factors 5. Patients who have participated in other interventional clinical trials within the past 30-90 days 6. Long-term alcoholics and drug abusers 7. Pregnant or lactating women 8. End-stage patients

Design outcomes

Primary

MeasureTime frame
Calprotectin;

Secondary

MeasureTime frame
IL-6/TNF-a;Exsome;MicroRNA;

Countries

China

Contacts

Public ContactZhang Shu

West China Hospital of Sichuan University

5042708@qq.com+86 189 8060 5699

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026