Lung mass
Conditions
Interventions
Sufentanil group:Using Sufentany as the main drug for intravenous patient-controlled analgesia
Teglitide Group:Using Teglitide as the main drug for intravenous patient-controlled analgesia
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. ASA classification I–III, age 18–75, no gender limitation; 2. Planned VATS lobectomy; 3. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergy to opioids or tapentadol; 2. Severe liver or kidney dysfunction (Child-Pugh class C or eGFR <30 mL/min/1.73m²); 3. Long-term use of opioids or analgesics before surgery; 4. Severe cardiovascular or pulmonary diseases (e.g., NYHA class III-IV heart failure or COPD GOLD III-IV); 5. Pregnant or breastfeeding women; 6. Preoperative consciousness disorders; 7. Refusal of participation by the patient or family members.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity within 48 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Drainage Tube Tolerance Index;Patient recovery quality;Pain intensity within 6/12/24 hours after surgery was assessed using the Visual Analog Scale (VAS);;ncidence of respiratory depression within 48 hours postoperatively;Patient satisfaction scores within 48 hours post-surgery;Use rate and dosage of rescue analgesics within 48 hours post-surgery; | — |
Countries
China
Contacts
Public ContactLiu Jun
epartment of Anesthesiology, 8th Floor, Building 7, 600 Tianhe Road, Tianhe District, Guangzhou City
Outcome results
None listed