Exploring the effectiveness of a Psychotherapy Chatbot (Nancy) for Improving Adult Mental Health: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600121508

Enrollment

Unknown

Registered

2026-03-31

Start date

2026-03-31

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

experimental group (Nancy):Psychotherapy Chatbot "Nancy" is trained on PsyLLM to improve mental health well-being among adults. PsyLLM is a domain-specific large language model for psychological couns

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Adults aged from 18 to 34 years; 2. No dyslexia; 3. Able to read Chinese; 4. Provided their informed consent.

Exclusion criteria

Exclusion criteria: 1.current suicidal ideation with intent and/or plan, or acute suicide risk (as indicated by screening assessment); 2.current or past psychotic disorder (self-reported clinician diagnosis or current treatment for psychosis).

Design outcomes

Primary

Measure	Time frame
9-item Patient Health Questionnaire;	—

Secondary

Measure	Time frame
Generalized Anxiety Disorder-7;Positive and Negative Affect Schedule;Usability Metric for User Experience–LITE;Barrett-Lennard Relationship Inventory Mandarin-Chinese version;	—

Countries

China

Contacts

Public ContactZhu Ningxin

The Chinese University of Hong Kong, Shenzhen

225030315@link.cuhk.edu.cn+86 186 8067 4115

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026