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Clinical study on the effects of transcranial alternating current stimulation on post-stroke executive impairment

Clinical study on the effects of transcranial alternating current stimulation on post-stroke executive impairment

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121506
Enrollment
Unknown
Registered
2026-03-31
Start date
2026-03-31
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke executive impairment (PSEI)

Interventions

Sponsors

Xuzhou Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosis met the criteria for stroke established by the Cerebrovascular Disease Study Group of the Chinese Society of Neurology, Chinese Medical Association (2019); 2.A score below 26 on the Montreal Cognitive Assessment (MoCA), with a sub-score of <4 (out of 5) on the visuospatial/executive function domain of the MoCA; 3.A score below 12 on the Frontal Assessment Battery (FAB); 4.Have sufficient visual and auditory resolution to accept neuropsychological tests, near-infrared functional tests and EEG tests; 5.Patients with first-ever stroke, within one year post-stroke, and in a stable medical condition; 6.The subject and/or guardian informed consent and signed the consent form; 7. Aged 40–75;

Exclusion criteria

Exclusion criteria: 1.Patients with executive dysfunction caused by diseases other than stroke, such as Alzheimer's disease, Lewy body disease, traumatic brain injury, infections, and alcohol abuse; 2.A personal or family history of epilepsy or psychiatric disorders; 3.Contraindications to tACS treatment, including patients with intracranial metal implants, or those with hyperalgesia, injury, or inflammation in the stimulation area; 4.Severe visual, cognitive, or verbal communication impairments that prevent cooperation with assessment and treatment; 5.Unstable medical condition, or concurrent severe somatic diseases;

Design outcomes

Primary

MeasureTime frame
Frontal Assessment Battery,FAB;

Secondary

MeasureTime frame
EEG signal;Montreal Cognitive Assessment Scale;Trail Making Test-B, TMT-B;Digit span test,DST;Functional Near-Infrared Spectroscopy detection;

Countries

China

Contacts

Public Contactwangshiyan

Xuzhou Rehabilitation Hospital

wangshiyan3669@163.com+86 18112007636

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026