Post-stroke executive impairment (PSEI)
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Diagnosis met the criteria for stroke established by the Cerebrovascular Disease Study Group of the Chinese Society of Neurology, Chinese Medical Association (2019); 2.A score below 26 on the Montreal Cognitive Assessment (MoCA), with a sub-score of <4 (out of 5) on the visuospatial/executive function domain of the MoCA; 3.A score below 12 on the Frontal Assessment Battery (FAB); 4.Have sufficient visual and auditory resolution to accept neuropsychological tests, near-infrared functional tests and EEG tests; 5.Patients with first-ever stroke, within one year post-stroke, and in a stable medical condition; 6.The subject and/or guardian informed consent and signed the consent form; 7. Aged 40–75;
Exclusion criteria
Exclusion criteria: 1.Patients with executive dysfunction caused by diseases other than stroke, such as Alzheimer's disease, Lewy body disease, traumatic brain injury, infections, and alcohol abuse; 2.A personal or family history of epilepsy or psychiatric disorders; 3.Contraindications to tACS treatment, including patients with intracranial metal implants, or those with hyperalgesia, injury, or inflammation in the stimulation area; 4.Severe visual, cognitive, or verbal communication impairments that prevent cooperation with assessment and treatment; 5.Unstable medical condition, or concurrent severe somatic diseases;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frontal Assessment Battery,FAB; | — |
Secondary
| Measure | Time frame |
|---|---|
| EEG signal;Montreal Cognitive Assessment Scale;Trail Making Test-B, TMT-B;Digit span test,DST;Functional Near-Infrared Spectroscopy detection; | — |
Countries
China
Contacts
Xuzhou Rehabilitation Hospital