postoperative delirium
Conditions
Interventions
TMS group:The patient received a 20-minute rTMS treatment once the day before surgery and once after extubation in the PACU.
control group:The patient undergoes the same RMT measurement, with a similar coil position, but no active stimulation is performed.
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age 65 years or older; 2. Duration of THA surgery between 60 to 180 minutes; 3. ASA classification I-III; 4. Education level of elementary school or above; 5. Montreal Cognitive Assessment score =26 points (add 1 point for those with =12 years of education); 6. Normal speech and hearing, able to cooperate with rehabilitation assessment and treatment.
Exclusion criteria
Exclusion criteria: 1. Known drug allergies, severe cardiovascular diseases, or liver and kidney dysfunction; 2. Use of sedative-hypnotics or drugs with anticholinergic effects that cannot be discontinued for at least four weeks prior to baseline; 3. rTMS contraindications: such as a history of epilepsy, cochlear implants, metal implants in the head, or pacemakers; 4. Currently participating in other clinical trials; 5. The participant or their legal representative is unable or unwilling to provide written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium within 3 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| subtypes of delirium;side effects;Pain score NRS 1-3 days post-surgery;Anxiety score (SAS) and depression score (SDS) one day after surgery; | — |
Countries
China
Contacts
Public ContactLiwei Wang
Xuzhou Central Hospital
Outcome results
None listed