Neonatal Necrotizing Enterocolitis
Conditions
Interventions
Gold Standard:The NEC group was divided into three subgroups according to Bell's staging criteria.
Index test:Extraction of peripheral blood LAND-Vs: Centrifuge at 300 g for 5 minutes, then centrifuge the supernatant at 3000 g for 5 minutes. Discard the supernatant, and the precipitate obtained is
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Inclusion criteria for the control group: Preterm infants hospitalized with a gestational age < 37 weeks, matched with the NEC group for gestational age (±1 week), birth weight (±100g), postnatal age (±1 week), and feeding method. 2.Inclusion criteria for the NEC group: Preterm infants hospitalized with a gestational age < 37 weeks, who meet the diagnostic criteria for NEC and are confirmed by at least two neonatologists to have modified Bell's staging stage I or higher.
Exclusion criteria
Exclusion criteria: 1.Exclusion criteria included: inflammatory diseases (such as pneumonia, sepsis, septicemia, peritonitis, etc.), allergic diseases (allergic enteritis, etc.), congenital gastrointestinal malformations (intestinal atresia, intestinal malrotation, gastric perforation, spontaneous intestinal perforation, etc.), complex congenital heart disease, chromosomal abnormalities, congenital genetic metabolic diseases, and infants who were withdrawn from treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Large Aging Neutrophil-Derived Vesicles,LAND-Vs; | — |
Countries
China
Contacts
Public ContactChunbao Guo
Chongqing Health Center for Women and Children
Outcome results
None listed