Laparoscopic resection of liver tumor
Conditions
Interventions
Control group :Remote Ischemic Conditioning (at the time point of 30 min after the start of the surgery, 9:00-10:00 am on postoperative day 1 and day 2): Three cycles (30 minutes), each consisting of
Rhythm group:Remote Ischemic Conditioning (7:00-8:00 am on the day of surgery, postoperative day 1, and postoperative day 2): Three cycles (30 minutes), each consisting of five minutes of cuff inflati
Sponsors
Yongchuan Hospital Affiliated to Chongqing Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective partial liver resection; 2. American Society of Anesthesiology (ASA) classification levels II-III; 3. Age between 25 and 75 years old; 4. New York Heart Association (NYHA) classification levels I-III.
Exclusion criteria
Exclusion criteria: 1. Patients with limb impairments or those suffering from peripheral vascular diseases that affect upper limb function; 2. Patients with a history of neurological, immune system, or mental disorders; 3. Patients who have previously undergone liver resection, have recent significant organ diseases, or have undergone surgical treatment; 4. Patients who have recently used anti-inflammatory analgesics, anticoagulants, hormone drugs, immunosuppressants, ATP-sensitive K-channel blockers (KATP); 5. Patients with severe preoperative renal insufficiency (serum creatinine > 442 umol/L, with or without serum potassium > 6.5 mmol/L, or if the clinician deems it necessary for renal replacement therapy), or liver insufficiency (Child-Pugh grade C); 6. Patients and/or their family members refuse to participate in this project.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glutamic-pyruvic transaminase, ALT;Operation time, blood loss and other surgical indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glutamic oxalacetic transaminase, AST;leukocyte, WBC;Neutrophil granulocyte percentage;Tumor necrosis factor-a, TNF-a;Per2;Hypoxia inducible factor-1 alpha, HIF-1a;Intestinal fatty acid-binding protein, I-FABP;Time to gastrointestinal tolerance;Prolonged postoperative ileus;Postoperative duration of hospital stay;Postoperative complications; | — |
Countries
China
Contacts
Public ContactChun Tian
Yongchuan Hospital Affiliated to Chongqing Medical University
Outcome results
None listed