Breast cancer
Conditions
Interventions
Observation Group:None
Sponsors
Henan Provincial People's Hospita,medical
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Specimens consisted of surgically resected breast cancer tissues, pathologically diagnosed as HR+/HER2- breast cancer by pathologists, with complete clinical and pathological data. 2.Formalin-fixed, paraffin-embedded (FFPE) blocks were in good condition, with adequate remaining tissue to allow serial sectioning (>=3 sections, 4 µm each).
Exclusion criteria
Exclusion criteria: 1.Specimens were excluded if sections exhibited severe antigen or nucleic acid degradation resulting from long-term storage, or if clinical or pathological information was incomplete. 2.Specimens were excluded in cases of staining failure or insufficient evaluable data for interpretation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Agreement (Cohen's Kappa);Positive Percent Agreement (PPA);Negative Percent Agreement (NPA);Overall Percent Agreement (OPA);Inter-rater Agreement (Fleiss' Kappa);Sensitivity;Specificity;Accuracy;Consistency of Immunohistochemistry Staining Intensity Scores between Two PTEN Antibodies; | — |
Countries
China
Contacts
Public ContactShi Yujie
Henan Provincial People's Hospita,medical
Outcome results
None listed