Preeclampsia
Conditions
Interventions
Normal pregnancy control group:None
Sponsors
Fuzhou University Affiliated Provincial Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Peripheral blood and placenta samples were collected from pregnant women with preeclampsia who delivered at the South Campus of Fuzhou University Affiliated Provincial Hospital. The control group consisted of 30 women who underwent elective cesarean section without any pregnancy complications during the same period. The diagnostic criteria for preeclampsia were based on the 9th edition of "Obstetrics and Gynecology". The study was approved by the hospital's ethics committee, and the subjects signed informed consent forms.
Exclusion criteria
Exclusion criteria: 1.With underlying conditions such as chronic hypertension, diabetes, nephropathy, or immune system diseases, in addition to other obstetric comorbidities and complications. 2.Assisted Reproductive Technology; 3.Multiple pregnancy (carrying two or more fetuses);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels of PAK6, SIRT4, and SLC25A5 in placental tissue and plasma, as well as apoptosis in placental tissue and CD4+ T cell differentiation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Child growth and development;Child growth and development; | — |
Countries
China
Contacts
Public ContactRong Lin
Fuzhou University Affiliated Provincial Hospital
Outcome results
None listed