Sedatives, hypnotic and anxiolytic dependence
Conditions
Interventions
Accelerated iTBS group:Participants randomised to the intervention group will receive accelerated intermittent Theta Burst Stimulation (iTBS) by MagVenture MagPro X100 stimulator according to a struct
total 600 pulses per session).
Intensity: 80% - 120% of the participant’s resting motor threshold, determined at baseline, in accordance with contemporary TMS safety guidelines.
Session duration: 3 mi
immediate cessation criteria and an on-site emergency protocol will be in place for any emergent adverse events, including suspected seizure activity.
Sham iTBS group:Participants assigned to the control group will receive a sham-controlled iTBS by an identical-looking MagVenture Placebo B70 Active / Placebo coil. This placebo coil is specifically d
Sponsors
Tai Po Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Age over 18 or above Hong Kong residents; 2. Diagnosed of sedatives, hypnotic and anxiolytic dependence in the Diagnostic and Statistical Manual – Fourth version (text revised) (DSM-IV-TR) / fifth version (DSM-V), or International Classification of Diseases – 10th (ICD-10) / 11th version (ICD-11) 3. Able to give written consent as recommended by the psychiatrist
Exclusion criteria
Exclusion criteria: 1. Being pregnant 2. Have a history of traumatic brain injury, seizures, or mania/hypomania 3. Have organic psychiatric disorder AND / OR learning disability 4. Have visual, language or communication difficulties 5. Have concomitant dependent to other abused substance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese version of the Craving Beliefs Questionnaire scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index; Chinese version of the 21-item Depression, Anxiety, and Stress Scale (DASS-21);Timeline Followback;Contemplation ladder; | — |
Countries
China
Contacts
Public ContactIP CHI KIN
Nurse Consultant
Outcome results
None listed