Perioperative elderly patients with mild cognitive impairment
Conditions
Interventions
acupuncture group:Patients in the electroacupuncture (EA) group received electroacupuncture preconditioning 30 minutes before surgery by qualified physicians holding dual licenses in Western medicine
non-acupuncture group:Non-acupuncture group patients underwent direct combined intravenous-inhalation general anesthesia with endotracheal intubation in the operating room without prior electroacupunc
Sponsors
Shenzhen People 's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 65 years and older; 2. Patients diagnosed with mild cognitive impairment (MCI) preoperatively; 3. American Society of Anesthesiologists (ASA) physical status Grade I–II; 4. Scheduled for elective lower extremity joint replacement surgery (total knee arthroplasty or total hip arthroplasty).
Exclusion criteria
Exclusion criteria: 1. Patients with absolute contraindications to combined intravenous-inhalation general anesthesia; 2. Patients complicated with severe cardiovascular, cerebrovascular, pulmonary, hepatic, renal, hematopoietic or neurological diseases, as well as malignant tumors; 3. Patients with psychiatric disorders other than MCI (e.g., severe schizophrenia, intellectual disability) or those unable to communicate due to hearing impairment, visual impairment or other causes; 4. Refusal to sign the informed consent form; 5. Long-term use of sedative or analgesic medications; 6. Skin damage or infection at the acupuncture sites.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of Postoperative Delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Phosphorylated Tau at Threonine 217;Montreal Cognitive Assessment;Mini-Mental State Examination;Visual Analogue Scale; | — |
Countries
China
Contacts
Public ContactZhongliang Dai
Shenzhen People's Hospital
Outcome results
None listed