Nicotine dependence
Conditions
Interventions
cTBS group:targeting the bilateral orofacial motor cortex using standard cTBS protocol
Sham group:Sham stimulation using coil-tilt method to minimize participants’ awareness of stimulation intensity and location
Sponsors
Shanghai University of Sport
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–50 years; 2. Smoke >=10 cigarettes per day and have a smoking history >=2 years; 3. Voluntarily participate and sign written informed consent; 4. Able to complete 5 days of intensive treatment on schedule and return for follow-up.
Exclusion criteria
Exclusion criteria: 1. History of epilepsy or seizures, or a family history of uncontrolled epilepsy; 2. Cranial/neck metal implants, pacemakers, and other TMS contraindications; 3. Severe mental illness (such as uncontrolled schizophrenia, major depression with risk of self-harm); 4. Women who are pregnant or breastfeeding; 5. Recent use of drugs that significantly alter cortical excitability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in subjective smoking craving ratings (VAS, 0-100);Self-reported number of cigarettes smoked in the 24 hours before and after intervention; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in QSU-Brief questionnaire scores;Changes in MNWS questionnaire scores;Response rate ; | — |
Countries
China
Contacts
Public ContactJian Zhang
Shanghai University of Sport
Outcome results
None listed