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Effect of Intratracheal Lidocaine via an Anti-Choking Double-Lumen Tube on Emergence Coughing After Thoracoscopic Lung Resection: An Exploratory Study

Effect of Intratracheal Lidocaine via an Anti-Choking Double-Lumen Tube on Emergence Coughing After Thoracoscopic Lung Resection: An Exploratory Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121397
Enrollment
Unknown
Registered
2026-03-30
Start date
2026-03-30
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough

Interventions

Normal saline intervention group:Injection of 10 mL of normal saline via a drug-delivery double-lumen endotracheal tube
Lidocaine intervention group:Injection of 10 mL of 1% lidocaine via a drug-delivery double-lumen endotracheal tube

Sponsors

Huadong Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled to undergo thoracoscopic lung resection; 2. Age = 18 years; 3. ASA I–III; 4. Mallampati class I–III; 5. BMI 18–28 kg/m².

Exclusion criteria

Exclusion criteria: 1. Chronic persistent cough; 2. Presence of upper respiratory tract infection within the past 2 weeks; 3. Severe gastroesophageal reflux; 4. Long-term use of ACEI with concurrent dry cough; 5. Requirement for tubeless procedure; 6. Presence of airway anatomical variations such as tracheal bronchus; 7. History of lidocaine allergy; 8. Currently in the acute phase of asthma attack.

Design outcomes

Primary

MeasureTime frame
Maximum emergence cough score;

Secondary

MeasureTime frame
The total number of mild choking coughs occurred;The total number of occurrences of moderate to severe choking coughs;The highest choking cough score before extubation;The highest score for choking and coughing during extubation;The highest score for choking and coughing after extubation;Extubation time;Tube removal quality score;Pipeline removal quality scoring system;The number of choking coughs or restlessness that require intervention during the awakening period;PACU stay time;Outpatient recovery room sore throat score;Cough score in the recovery room;Score for hoarseness of voice upon awakening;Throat pain score 24 hours after surgery;Cough score 24 hours after surgery;Postoperative 24-hour voice hoarseness score;

Countries

China

Contacts

Public ContactGu Weidong

Huadong Hospital Affiliated to Fudan University

shirley212zhr@163.com+86 21 6248 3180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026