Glioma
Conditions
Interventions
Glioma patients:None
Sponsors
Beijing Neurosurgical Institute
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with histologically or cytologically confirmed high-grade glioma. 2. At the time of signing the informed consent form, patients must be aged >=18 and =70 prior to treatment. 4. Patients agree to provide clinical and treatment-related information and may participate in study visits, laboratory tests, and other research-related procedures.
Exclusion criteria
Exclusion criteria: 1. Presence of another concurrent malignant tumor. 2. Lack of a detailed histopathological diagnostic report to determine the nature of the lesion. 3. Any severe and/or uncontrolled comorbid medical condition that, in the investigator’s judgment, may affect the patient’s participation in the study or interfere with the study results. 4. Any social or psychological issues that, in the investigator’s judgment, render the patient unsuitable for participation in this study. 5. Inability to undergo surgery and adjuvant therapy at the current medical institution followed by long-term, regular follow-up. 6. Unwillingness or inability to comply with the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exosomal miRNA expression levels in cerebrospinal fluid;EGFR mutation expression (EGFRvIII);VEGF-A alternative splicing (ratio of VEGF165b to VEGF165 in VEGF-A);Postoperative survival duration; | — |
Countries
China
Contacts
Public ContactZhang Junwen
Beijing Neurosurgical Institute
Outcome results
None listed