None
Conditions
Interventions
Observation group:None
Sponsors
Hangzhou Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. 18-55 years of age, scheduled for elective surgery (e.g. plastic/cosmetic surgery); 2. Conscious and fully capable of civil conduct, able to understand the research content and voluntarily sign a written informed consent form. 3. Based on routine hospital examinations prior to surgery, there is no active systemic severe infection. 4. The skin appearance in the surgical area is generally normal, with no signs of acute suppurative infection, severe eczema, or extensive skin ulcers. 5. Consent to the use of discarded skin tissue from their surgery for this study, and consent to its use in in vitro experimental research after de-identification.
Exclusion criteria
Exclusion criteria: 1.Individuals who are unable to fully comprehend research information, or who have mental or cognitive impairments that prevent them from expressing their true wishes. 2.The surgical site exhibits significant acute suppurative infection, severe skin inflammation, malignant tumors, or suspected malignant lesions. 3.Patients with a history of severe hemorrhagic disorders or significant coagulation abnormalities requiring modification of surgical approach or resection extent. 4.Patients with severe systemic diseases (such as decompensated cardiac, hepatic, or renal insufficiency) identified during preoperative assessment, resulting in significantly higher surgical risks than the general population. 5.Individuals known to have HIV infection or other highly infectious diseases, whose tissue is not clinically recommended for inclusion in standard laboratory procedures. 6.Individuals unwilling to participate in this study or who refuse to sign the informed consent form; 7.Other circumstances deemed unsuitable for participation in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Keratinocyte markers K14/K10;Fibroblast marker vimentin; | — |
Countries
China
Contacts
Public ContactZhang Zuyong
Hangzhou Third People's Hospital
Outcome results
None listed