Chest distress
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) American Society of Anesthesiologists (ASA) grade II-III. (2) singleton full-term pregnancy (>=37 weeks); (3) Cesarean section under spinal anesthesia (or combined spinal-epidural anesthesia). (4) Informed consent was signed. (5) Age 20-40 years old.
Exclusion criteria
Exclusion criteria: (1) Allergic to nalbuphine, opioids or carboprost. (2) History of severe gestational hypertension, heart disease, asthma, or glaucoma; (3) Fetal distress, placenta previa, placental abruption and other situations requiring emergency delivery of the fetus. (4) patients had nausea, vomiting or used antiemetic drugs before surgery. (5) patients had a history of opioid abuse or long-term use of analgesics. (6) severe abnormal liver function (anesthesiologists judged that nalbuphine was not suitable for use).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chest distress; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomiting;Blood pressure;Heart rate;Dyspnea;Postoperative pain; | — |
Countries
China
Contacts
Wuxi Huishan District People's Hospital