Pituitary adenoma
Conditions
Interventions
Tegileridine group :Tegilildine was pumped intravenously after pituitary tumor resection
Sufentanil group:Sufentanil was pumped intravenously after pituitary tumor resection
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Patients scheduled for endoscopic transnasal pituitary tumor resection surgery; 2. Age between 18 and 70 years; 3. ASA classification of grade II-III; 4. Voluntary participation and signing of informed consent form
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Patients who have undergone a second surgery; 2. Patients allergic to any component of opioids or the test drug; 3. Patients with abnormal liver or kidney function; 4. Patients who have used antiemetic drugs or glucocorticoids within 24 hours before the surgery; 5. Patients who have been chronically using opioids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative 24-hour Pain Relief Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative respiratory depression;The incidence of nausea and vomiting within 48 hours after surgery;Postoperative sore throat;Postoperative catheter-related bladder discomfort;Adverse reactions;Rescue Analgesia Frequency and Time to First Rescue;Baseline measures; | — |
Countries
China
Contacts
Public ContactKang Fang
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed