Elderly patients with atrial fibrillation
Conditions
Interventions
Group S:Sufentanil Citrate Group
Group B:Butorphanol tartrate group
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.First-time one-stop service for atrial fibrillation patients; 2.Patients aged 65 years or older; 3.ASA Grade I–III; 4.BMI 18–30 kg/m^2; 5.Heart function class I–II; 6.Voluntary Informed Consent;
Exclusion criteria
Exclusion criteria: 1.Drug allergies used in this research; 2.Preoperative assessment revealed cognitive impairment (MMSE < 24). 3.Individuals with central nervous system (CNS) disorders or taking psychiatric medications; 4.Individuals with brain injury and elevated intracranial pressure; 5.Patients with a history of drug use; 6.Severe pulmonary disease (PaO2 < 60 mmHg), cardiovascular disease (NYHA Class III), and hepatic/renal dysfunction (Child-Pugh Class C, CKD Stage 4);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium on the first day; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality;Anxiety Self-Assessment, Depression Self-Assessment, Pittsburgh Sleep Quality Index;Postoperative pain (NRS score) and adverse reactions such as PONV;Inflammatory markers;Surgery duration, propofol dosage, methoxamine dosage (infusion rate and rescue dose);Hemodynamic parameters and BIS values; | — |
Countries
China
Contacts
Public ContactSun Defeng
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed