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IOP Prediction Model Using Corneal Morphology and Biomechanics in Children Post-Cataract Surgery.

IOP Prediction Model Using Corneal Morphology and Biomechanics in Children Post-Cataract Surgery.

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121312
Enrollment
Unknown
Registered
2026-03-30
Start date
2026-03-30
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Conditions: Pediatric Cataract, Glaucoma. Clinical Presentation: Pediatric cataract, a lens opacity occurring from birth through childhood, impairs visual development. It presents with pupillary opacity, reduced vision, strabismus, and nystagmus, potentially leading to amblyopia or blindness. Post-cataract surgery, elevated intraocular pressure (IOP) increases glaucoma risk, affecting ~32% of apha

Interventions

control:NA.
primary IOL implantation:Performed combined lensectomy, anterior vitrectomy, posterior capsulotomy, and primary intraocular lens (IOL) implantation surgery.
secondary IOL implantation:Performed combined lensectomy, anterior vitrectomy, posterior capsulotomy, and secondary intraocular lens (IOL) implantation surgery.

Sponsors

Eye Hospital, Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1.Children diagnosed with congenital or developmental cataract who have undergone surgical treatment at our hospital. 2.Healthy children. 3.Age >= 5 years and <18 years. 4.Capable of cooperating with routine ophthalmic examinations and Corvis ST measurements, and willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Marked nystagmus preventing reliable ocular examination. 2.Concurrent ocular pathology (e.g., aniridia, microcornea, retinal detachment). 3.Associated systemic disorders (e.g., Down syndrome, Marfan syndrome). 4.History of ocular trauma or prior intraocular surgery. 5.Recent (within 3 months) use of topical ophthalmic medications or contact lenses.

Design outcomes

Primary

MeasureTime frame
Corrects intraocular pressure;Corneal biomechanical parameters;

Secondary

MeasureTime frame
Corneal morphological parameters;

Countries

China

Contacts

Public ContactZiqi Meng

Eye Hospital, Wenzhou Medical University

mzqxyxgz@126.com+86 577 88053521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026