Effect of Liposomal Bupivacaine for Pericapsular Nerve Group Block Combined with Lateral Femoral Cutaneous Nerve Block on postoperative motor-sparing analgesia in patients undergoing hip arthroplasty

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600121298

Enrollment

Unknown

Registered

2026-03-27

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hip arthroplasty

Interventions

Experimental group:Liposomal Bupivacaine for Pericapsular Nerve Group Block Combined with Lateral Femoral Cutaneous Nerve Block

control group:Ropivacaine hydrochloride for Pericapsular Nerve Group Block Combined with Lateral Femoral Cutaneous Nerve Block

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective primary unilateral hip arthroplasty; 2. Age range 19–80 years; 3. ASA (American Society of Anesthesiologists) Classification I–III; 4. Body mass index (BMI): 18–30 kg/m²; 5. Informed consent form signed by the patient.

Exclusion criteria

Exclusion criteria: 1. Ankylosis of the hip joint; 2. Allergy to the drugs used in the study; 3. Opioid or alcohol abuse or dependence; 4. Contraindications to nerve block; 5. History of cerebral infarction and related sequelae; 6. Neuromuscular disease; 7. Previous open hip surgery; 8. Other neurological disorders affecting the hip joint; 9. Severe hearing, vision, or mental disorders that prevent effective communication, or cognitive impairment as indicated by the Mini-Mental State Examination (MMSE) score; 10. Complicated by severe cardiopulmonary disease, hepatorenal insufficiency, or severe arrhythmias requiring treatment; 11. Refusal to use a patient-controlled intravenous analgesia (PCIA) pump after surgery.

Design outcomes

Primary

Measure	Time frame
Dynamic Numeric Rating Scale (NRS) scores at 48 hours postoperatively;	—

Secondary

Measure	Time frame
Static and dynamic pain scores at different time points after surgery;Quadriceps muscle strength at different time points after surgery;Postoperative lower limb motor function;Incidence of postoperative complications;Quality of early postoperative recovery;Cumulative opioid consumption after surgery;Total length of hospital stay;	—

Countries

China

Contacts

Public ContactLei Cao

The Central Hospital of Wuhan

caolei22577@163.com+86 27 8221 1435

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026