Upper limb motor dysfunction following stroke
Conditions
Interventions
Joint Group:During intervention, peripheral magnetic stimulation is performed first, followed by transcranial magnetic stimulation, with an interval within the effective delay effect of the stimulatio
Itbs Group:Perform peripheral magnetic stimulation sham stimulation first, followed by ITBS stimulation.
Peripheral magnetic stimulation Group:Perform peripheral magnetic stimulation first, followed by ITBS sham stimulation.
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. It conforms to the stroke diagnosis criteria set forth in the "Guidelines for the Prevention and Treatment of Cerebrovascular Diseases" (2024 Edition) [1] and is supported by imaging evidence. 2. The first onset was characterized by hemiplegia on one side of the body and motor dysfunction of the upper limbs. 3. The duration of the illness ranges from 2 weeks to 12 months. The condition is stable and the patient is able to cooperate with the treatment and assessment. 4. Age 18-80 years; 5. The upper limb is in the Brunnstrom stage between I and IV. 6. The patient himself/herself or their family members understand and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. There are contraindications for transcranial magnetic stimulation: individuals with epileptic seizures or a family history of epilepsy; those with severe or unstable heart conditions (such as myocardial infarction within 6 months, unstable angina pectoris, NYHA cardiac function class III or above, severe arrhythmia, etc.); or those with known coagulation disorders, bleeding disorders (such as hemophilia), or a history of platelet count lower than 100×10?/L; or those with other uncontrolled severe internal medical conditions (such as decompensated liver cirrhosis, end-stage renal disease, poorly controlled severe hypertension, etc.); patients with open wounds locally, infected areas, implanted cardiac pacemakers, cochlear implants, metal implants in the brain, or those using artificial materials to repair the skull; 2. Those who have fear or intolerance towards transcranial magnetic stimulation; 3. Patients who are unable to cooperate with doctors or therapists, and have poor compliance; 4. Those who have experienced motor function impairment due to other pre-existing diseases; 5. Those who are pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer assessment of upper extremity motor function;Modified Barthel Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index;Brain Symmetry Index;DTABR((d+?)/(a+ß));Health Status Questionnaire;Action Research Arm Test;DAR(d/a);Self-Rating Anxiety Scale;Self-Rating Depression Scale; | — |
Countries
China
Contacts
Public ContactJunwei Zong
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed