Induced Abortion
Conditions
Interventions
Test group:The patient was placed in the lithotomy position. Oliceridine was administered intravenously, followed by slow intravenous injection of ciprofol 0.4 mg/kg. A vaginal speculum was inserted a
if a negative response occurred, the dose was decreased by 0.002 mg/kg.
Sponsors
General Hospital of Northern Theater Command
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade I or II; 2. Aged 20–45 years; 3. BMI 18.5–26.0 kg/m²; 4. Transvaginal ultrasound confirmed early intrauterine pregnancy and scheduled for painless induced abortion under general anesthesia; 5. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Acute upper respiratory tract infection; 2. Full stomach (not fasting as required); 3. Severe dysfunction of vital organs, including severe cardiac, pulmonary, hepatic, or renal impairment; 4. Hypertension or cardiac arrhythmia; 5. Anticipated difficult airway; 6. Long-term use of psychotropic medications or presence of cognitive dysfunction; 7. Allergy or contraindication to any medication used in the planned anesthesia regimen; 8. Expected or actual surgical duration > 10 minutes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A positive response was defined as the occurrence of body movement during cervical dilatation (including frowning, moaning, or involuntary limb movement), or an increase in heart rate (HR) or mean arterial pressure (MAP) exceeding 20% of the baseline value.;ED50;ED95; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean Arterial Pressure (MAP);Oxygen Saturation (SpO2);Duration of surgery;Duration of anesthesia;Recovery time;Ciprofol consumption;Pain VAS score at 15 minutes after awakening; | — |
Countries
China
Contacts
Public ContactLi Lin
Department of Anesthesiology, General Hospital of Northern Theater Command
Outcome results
None listed