Glucocorticoid-associated femoral head necrosis
Conditions
Interventions
Retrospective Cohort (Sun Yat-sen University Cancer Center):None
Retrospective Cohort (Shenshan Central Hospital):None
Prospective Cohort (Sun Yat-sen University Cancer Center):None
Prospective Cohort (Shenshan Central Hospital):None
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 18 and 60 years. 2.Diagnosed with osteonecrosis of the femoral head (ONFH) at ARCO stage II Documented history of glucocorticoid use. 3.Availability of pre-treatment plain radiographs and MRI scans along with their corresponding reports. 4.Availability of standardized and complete clinical medical records. 5.Having undergone hip-preserving treatment (including non-surgical management, core decompression , or lesion debridement and bone grafting ). 6.Completion of a 2-year follow-up, or anticipated to reach the 2-year follow-up endpoint within 6 months prior to the project's conclusion.
Exclusion criteria
Exclusion criteria: 1.History of ipsilateral hip trauma or prior hip surgery; 2.Incomplete clinical or follow-up imaging data. 3.Occurrence of hip joint trauma during the follow-up period. 4.Comorbid psychiatric disorders. 5.Comorbid hip osteoarthritis. 6.Any other condition deemed by the investigator as unsuitable for study participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maintenance of ARCO stage II ONFH; | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory tests;Past medical history;Demographic characteristics;Genetic Information;Physical Examination;Radiographic Studies;Present illness; | — |
Countries
China
Contacts
Public ContactLi Deng
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed