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The Impact of the Timing of Carbon Nanoparticle Tracer Injection on Lymph Node Dissection during Laparoscopic Rectal Resection in Rectal Cancer Patients Undergoing Neoadjuvant Therapy

The Impact of the Timing of Carbon Nanoparticle Tracer Injection on Lymph Node Dissection during Laparoscopic Rectal Resection in Rectal Cancer Patients Undergoing Neoadjuvant Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121259
Enrollment
Unknown
Registered
2026-03-27
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

Pre-neoadjuvant carbon nanoparticle tracer injection group:Pre-neoadjuvant carbon nanoparticle tracer injection
Preoperative carbon nanoparticle tracer injection group:Preoperative carbon nanoparticle tracer injection

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with rectal cancer confirmed by colonoscopy and pathology, whose preoperative clinical stage was assessed by endoscopic ultrasonography and MRI, and who met the indications for neoadjuvant chemoradiotherapy; 2. Newly diagnosed patients who had not received any prior anti-tumor treatment; 3. Consent obtained from the patient or their legal guardian, and the informed consent form for the trial signed.

Exclusion criteria

Exclusion criteria: 1. Presence of distant organ metastasis or peritoneal metastasis. 2. Inability to tolerate chemoradiotherapy or surgical treatment. 3. Emergency conditions such as obstruction, bleeding, or perforation.

Design outcomes

Primary

MeasureTime frame
Number of lymph nodes dissected;3-year disease-free survival;

Secondary

MeasureTime frame
Staining rate of positive lymph nodes;Blood loss;Operation time;Postoperative complications;3-year local recurrence rate;

Countries

China

Contacts

Public ContactShen Shuai

Weifang People's Hospital

11510599328@qq.com+86 157 0542 8649

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026