Dermatomyositis
Conditions
Interventions
The group with negative TIF1-? antibody test result:None
The group with positive TIF1-? antibody observation:None
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with DM who have been clearly diagnosed according to the Bohn/Peter criteria; diagnosed with malignant tumors based on clinical, imaging or pathological evidence, and meeting the diagnostic criteria for all types of tumors; 2. The diagnosis of malignant tumors occurred within 3 years before or after the onset of DM; 3. Tumor paraffin specimens, blood samples and muscle tissues can be obtained; 4. Age range: 18-75 years old, gender not restricted.
Exclusion criteria
Exclusion criteria: 1. Include other connective tissue diseases (such as systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, Sjogren's syndrome); 2. Severe liver and kidney dysfunction (Child-Pugh grade B or C, creatinine >= 1.5 times the upper limit of normal)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The relationship between TIF1-? gene mutation and cross-immune response; | — |
Countries
China
Contacts
Public ContactYang Kanbo
China-Japan Friendship Hospital
Outcome results
None listed