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Correlation analysis between 12-HETE and slow flow/no-reflow phenomenon in patients with acute myocardial infarction after PCI

Correlation analysis between 12-HETE and slow flow/no-reflow phenomenon in patients with acute myocardial infarction after PCI

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600121229
Enrollment
Unknown
Registered
2026-03-27
Start date
2026-03-28
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

The non-surgical group:None

Sponsors

The First Hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All the included patients met the diagnostic criteria for acute myocardial infarction, and all of them underwent emergency PCI surgery. The diagnostic criteria for acute myocardial infarction conformed to the definition of acute myocardial infarction in the "Diagnosis and Treatment Guidelines for Acute ST-segment Elevation Myocardial Infarction" (2019 Edition): According to the fourth edition of the "Global Definition of Myocardial Infarction" standards, myocardial infarction refers to acute myocardial injury, elevated serum cardiac troponin (cardiac troponin, cTn), and/or a decrease, and at least once higher than the upper limit of the normal value (the 99th percentile value of the reference value), while there is clinical evidence of acute myocardial ischemia, including: (1) Acute myocardial ischemic symptoms; (2) New ischemic electrocardiogram changes; (3) New pathological Q waves; (4) New imaging evidence of loss of viable myocardium or segmental movement abnormalities of the ventricular wall; (5) Coronary angiography or intracardiac imaging examination or autopsy confirmed coronary artery thrombosis.

Exclusion criteria

Exclusion criteria: 1.Patients with onset time exceeding 48 hours; 2.Patients undergoing PCI after thrombolysis, emergency angiography only, or elective PCI; 3.Patients with comorbidities such as malignant tumors, severe hepatic or renal dysfunction, severe heart valve disease, or severe infections; 4.Patients with contraindications to antiplatelet and anticoagulant therapy, such as active gastrointestinal ulcer, severe coagulation dysfunction, or bleeding disorders; 5.Patients with allergies to contrast media or surgical materials;

Design outcomes

Primary

MeasureTime frame
12-HETE;

Countries

China

Contacts

Public ContactChunrong Jin

The First Hospital of Shanxi Medical University

jinchunrong525@sina.com+86 351 4639065

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026