Posterior circulation occlusion (vertebrobasilar occlusion), posterior circulation cerebral infarction
Conditions
Interventions
Endovascular therapy group:None
Non-endovascular therapy group:None
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 - 80 years old; 2. Meets the diagnostic criteria for posterior circulation ischemic stroke, with onset time <= 24 hours; 3. Imaging confirms occlusion of the intracranial segment of the vertebral artery or the basilar artery (CTA/MRA); 4. Planned for endovascular thrombectomy treatment, and the patient or their legal representative has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe bleeding tendency (such as coagulation dysfunction, active bleeding); 2. Severe underlying diseases (such as end-stage renal disease, advanced malignant tumors) with an expected survival period of less than 3 months; 3. Previous severe cognitive impairment (baseline MoCA score < 10); 4. Refusal to participate or inability to complete follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of favorable cognitive outcome at 3 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of symptomatic intracranial hemorrhage;90-day all-cause mortality;Neurological functional outcome;The endpoint of surgical effectiveness;Refined assessment of cognitive function;Safety and no-reflow end points;Quality of life endpoint; | — |
Countries
China
Contacts
Public ContactLe Weidong
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed