Peri-implant tissue defect
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years. 2. Single tooth loss in the anterior region treated with implant-supported restoration. 3. Presence of a buccal bone defect after implant placement, with the defect extent < 50% of the implant length (classified as a 1/4-type defect according to the Terheyden classification; Cordaro et al., 2019). 4. Patients who received guided bone regeneration (GBR) or connective tissue grafting (CTG) during implant placement or during the restorative phase. 5. Distance between the buccal surface of the implant and the theoretical buccal bone arch contour <= 2 mm. 6. Generally healthy or medically stable patients who can tolerate routine implant therapy.
Exclusion criteria
Exclusion criteria: 1. Presence of severe systemic diseases (e.g., uncontrolled diabetes mellitus or immune disorders). 2. Long-term use of medications that may affect bone metabolism or wound healing. 3. Heavy smoking or chronic alcohol abuse. 4. Poor oral hygiene or uncontrolled periodontal disease. 5. Pregnancy or history of radiotherapy in the head and neck region.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Linear and volumetric change of buccal soft tissue profile; | — |
Secondary
| Measure | Time frame |
|---|---|
| Midfacial recession;Pink Esthetic Score, PES;Mucosal Scarring Index, MSI;Implant survival;Marginal bone loss, MBL;Modified sulcus bleeding index, mSBI;Modified plaque index, mPI;Probing depth, PD; | — |
Countries
Chine
Contacts
West China Hospital of Stomatology, Sichuan University