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Early Open Diet After Endoscopic Mucosal Resection/Endoscopic Submucosal Dissection for Giant Colorectal Polyps: A Single-Center, Non-Inferiority, Randomized Controlled Trial

Early Open Diet After Endoscopic Mucosal Resection/Endoscopic Submucosal Dissection for Giant Colorectal Polyps: A Single-Center, Non-Inferiority, Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121216
Enrollment
Unknown
Registered
2026-03-26
Start date
2026-03-26
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal polyp

Interventions

Experimental Group 1:Initiating oral intake at 6 hours post-procedure
Experimental Group 2:Initiating oral intake at 12 hours post-procedure
Control Group:Initiating oral intake at 24 hours post-procedure

Sponsors

Drum Tower Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18-75 years, regardless of gender; 2.diagnosed with colorectal polyps measuring 20-50 mm in diameter; 3.meeting the indications for EMR/ESD; 4.patients voluntarily participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Concomitant gastroesophageal reflux disease or other colorectal disorders; 2.cirrhosis or coagulopathy with a bleeding tendency; 3.undergoing anticoagulant therapy prior to surgery; 4. previous history of colorectal surgery; 5. currently participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
Incidence of Post-procedural Hemorrhage;

Secondary

MeasureTime frame
Total medical costs;Postoperative abdominal pain score;Hospitalization duration;Incidence of Postoperative delayed perforation;

Countries

China

Contacts

Public ContactChen Min

Drum Tower Hospital

croweminchan@nju.edu.cn+86 25 83104616

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026