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Effect of Compound Chamomile and Lidocaine Hydrochloride Gel on Postoperative Pulmonary Complications in Elderly Patients Undergoing Tracheal Intubation for Laparoscopic Surgery: A Multicenter, Randomized, Parallel-Controlled Study

Effect of Compound Chamomile and Lidocaine Hydrochloride Gel on Postoperative Pulmonary Complications in Elderly Patients Undergoing Tracheal Intubation for Laparoscopic Surgery: A Multicenter, Randomized, Parallel-Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600121213
Enrollment
Unknown
Registered
2026-03-26
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications in elderly patients with tracheal intubation and laparoscopy

Interventions

Trial Group:Apply compound chamomile lidocaine gel to uniformly lubricate the cuff and tip of the endotracheal tube before intubation
Control Group:Apply normal saline to uniformly lubricate the cuff and tip of the endotracheal tube before intubation

Sponsors

Guangdong Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Planned tracheal intubation; elderly patients scheduled for laparoscopic surgery under general anesthesia; 2. No gender restriction; 3. Patients aged 65-85 years; 4. American Society of Anesthesiologists (ASA) classification I-III; 5. Body mass index (BMI) 18.5-29.9 kg/m^2; 6. No contraindications to the study drug; 7. Signed informed consent for the study.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; Patients who were converted to laparotomy during the operation; 2. Patients with a history of cardiothoracic surgery; 3. Severe lung disease (GOLD >2); 4. History of chest infection, sepsis, or severe neuromuscular disease; 5. Airway obstruction or pharyngeal abscess; 6. Allergy to drug components; 7. Anticipated difficult intubation; 8. Other individuals unsuitable for clinical trials

Design outcomes

Primary

MeasureTime frame
Lung Prognostic Score;

Secondary

MeasureTime frame
Postoperative acute pulmonary complications;Other related complications of orotracheal intubation;First-attempt intubation success rate;Number of intubations;Time of extubation;Length of hospital stay;Incidence of adverse events;

Countries

China

Contacts

Public ContactAi Juan

Department of Anesthesiology, University Town Hospital, Guangdong Hospital of Traditional Chinese Medicine

ajbbmm9@163.com+86 185 6525 6215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 4, 2026