Pulmonary complications after thoracic surgery
Conditions
Interventions
Experimental group:During the one lung ventilation, the fractional concentration of inspired oxygen (FiO2) was initially set at 60%, if the patient can maintain at SpO2>=92%, FIO2 was maintained at 10
Control group:During the one lung ventilation, the fractional concentration of inspired oxygen (FiO2) was initially set at 60%, if the patient can maintain at SpO2>=92%, it is maintained.
Sponsors
The First Affiliated Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for thoracoscopic lung (lobe, segment, wedge-shaped) resection; 2. Age >= 18 years old; 3. ASA classification I - III.
Exclusion criteria
Exclusion criteria: 1. During single-lung ventilation, the patient was unable to tolerate an oxygen concentration of 60%. 2. Unexpected bleeding occurred 7 days after the surgery. 3. History of lung surgery. 4. History of perioperative blood transfusion. 5. Patients with mental disorders who were difficult to cooperate. 6. Central nervous system diseases. 7. Liver and kidney dysfunction, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of first PPCs within 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diaphragm thickening fraction during tidal breathing;Diaphragm excursion during tidal breathing;Diaphragm thickening fraction during maximal inspiration;Diaphragm excursion during maximal inspiration;The incidence of PPCs;The incidence of other postoperative complicaitons;Cerebral oxygenation (rSO2); | — |
Countries
China
Contacts
Public ContactJiehao Sun
The First Affiliated Hospital, Wenzhou Medical University
Outcome results
None listed