Adenocarcinoma in situ, minimally invasive adenocarcinoma, and invasive adenocarcinoma
Conditions
Interventions
Patients with high-risk pulmonary nodules:None
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-80 years; 2.Able to provide CT imaging data (in DICOM format) and radiology reports obtained within 4 weeks before surgery or biopsy. The nodule must be assessed as high-risk (Lung-RADS category 4A or higher) on imaging, and the patient must be scheduled for either: Curative-intent surgical treatment, OR Further diagnostic procedures (e.g., tissue biopsy, PET-CT, contrast-enhanced CT) to determine eligibility for curative-intent surgery; 3.Able to provide a peripheral blood sample (approximately 10 mL) collected within 1 week before surgery or biopsy. 4.Able to provide complete medical history records (including age, gender, smoking history, family history of cancer, and personal history of lung diseases); 5.Has not received any prior anti-tumor therapy (such as radiotherapy, chemotherapy, targeted therapy, immunotherapy, or surgical resection) directed at the target nodule before the blood sample and CT imaging are obtained; 6.Voluntarily participates in the study and provides written informed consent.
Exclusion criteria
Exclusion criteria: 1.History of or concurrent malignancy at other sites (e.g., breast cancer, colorectal cancer); 2.Has undergone major surgery, experienced significant trauma, received a blood transfusion, or had an active infection within the past 3 months; 3.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Benign and malignant pulmonary nodules.; | — |
Countries
China
Contacts
Public ContactJixian Liu
Peking University Shenzhen Hospital
Outcome results
None listed