Primary Insomnia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. At least two weeks before this visit, there was primary insomnia, or long-term shift work, or habitual staying up late (for more than two weeks). 2. I have no history of any major underlying physical or mental illnesses (sleep disturbances require exclusion of organic or major psychiatric disorders; emotional fluctuations caused by life events leading to sleep disturbances can be retained, but stress-related spectrum disorders need to be excluded). 3. Within 3 months prior to the baseline follow-up, no long-term regular use (defined as use for more than one week after diagnosis) of immunosuppressants, metabolic regulatory drugs, hormone replacement drugs (sex hormones/thyroid hormones), antipsychotics, mood stabilizers, antidepressants, hypnotics, etc. (other drugs/non-drug supplements/Chinese medicine may be continued, but must be clearly noted at baseline). 4. No family history of major physical or mental illnesses; 5. Informed consent to participate in this follow-up cohort.
Exclusion criteria
Exclusion criteria: 1. All situations that do not meet the inclusion criteria; 2. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Metabolomics;Fecal 16S rRNA sequencing;Athens Insomnia Scale;Epworth Sleepiness Scale ;Bedtime Procrastination Scale; | — |
Countries
China
Contacts
Shandong Provincial Hospital