None
Conditions
Interventions
The fospropofol group (F ):After entering the room, intravenous access was opened, oxygen was inhaled through a mask (oxygen flow rate 6L/min), and local infiltration anesthesia with 2% lidocaine
La
Sufentanil Group (SF Group):After entering the room, a venous access was established and oxygen was inhaled through a mask (oxygen flow rate 6 L/min). A local infiltration anesthesia with 2% lidocaine
Sponsors
The Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 60-75 years, any gender; 2. American Society of Anesthesiologists (ASA) class I-II; 3. Patients scheduled for general anesthesia surgery; 4. Airway classification I-II; 5. Informed consent, voluntary participation in the trial, and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of severe cardiopulmonary disease; 2. History of central nervous system disease; 3. Presence of severe organic diseases, such as liver or kidney dysfunction; 4. History of asthma; 5. History of long-term use of sedatives and opioids, or drug allergies; 6. Known or suspected allergy to any components of the study drugs or to protocol-specified medications (such as sufentanil citrate injection, propofol disodium injection) or contraindications to them; 7. Difficult airway identified during preoperative assessment; 8. History of preoperative radiotherapy or chemotherapy; 9. Emergency surgery; 10. Subjects deemed by the investigator to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ED50;Patient's general condition before surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs;Sedation time;Adverse reaction; | — |
Countries
China
Contacts
Public ContactShen Junmei
The Fourth Hospital of Hebei Medical University
Outcome results
None listed